Outcome Of Hematopoietic Stem Cell Transplantation For Wiskott-Aldrich Syndrome
نویسندگان
چکیده
منابع مشابه
[Hematopoietic stem cell transplantation for patients with Wiskott-Aldrich syndrome].
BACKGROUND Wiskott-Aldrich syndrome (WAS) is an X linked congenital disease that presents as eczema, thrombocytopenia and immune deficiency. The only curative procedure for this illness is hematopoietic stem cell transplant (HSCT), preferably from a healthy HLA identical sibling donor. Cord blood is becoming an excellent alternative as stem cell source from unrelated donors. AIM To report our...
متن کاملBrief report Correction of the murine Wiskott-Aldrich syndrome phenotype by hematopoietic stem cell transplantation
Allogeneic hematopoietic stem cell transplantation (HSCT) corrects the WiskottAldrich syndrome (WAS) phenotype. However, the toxicity and mortality frequently associated with this approach warrant the exploration of new therapeutic strategies. Transplantation studies of a murine model of WAS deficiency have been limited by the occurrence of a radiationinduced fatal exacerbation of a preexisting...
متن کاملCorrection of the murine Wiskott-Aldrich syndrome phenotype by hematopoietic stem cell transplantation.
Allogeneic hematopoietic stem cell transplantation (HSCT) corrects the Wiskott-Aldrich syndrome (WAS) phenotype. However, the toxicity and mortality frequently associated with this approach warrant the exploration of new therapeutic strategies. Transplantation studies of a murine model of WAS deficiency have been limited by the occurrence of a radiation-induced fatal exacerbation of a pre-exist...
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ژورنال
عنوان ژورنال: Biology of Blood and Marrow Transplantation
سال: 2014
ISSN: 1083-8791
DOI: 10.1016/j.bbmt.2013.12.389